1978 a woman died of rabies due to a cornea transplant from an infected person.

Rabies is a deadly viral disease. This disease is zoonotic. Means disease caused from one species to another. Like, dogs, cats, horses, and mice and bats, etc., in humans. It is as deadly for humans as it is for animals. The rabies virus affects the central nervous system and the brain. As a result, man acts like an animal, is afraid of water, and is afraid of wind. react like a dog. In the end death, within 7 to 14 of the occurring of symptoms.

The rabies virus travels through the peripheral nerves to the brain. The incubation period of the disease is typically a few days to a few months in humans, depending on the site and severity of exposure, the distance the virus must travel to reach the central nervous system.

The virus multiplies in muscle tissue and then spread rapidly to the neural pathways.


The initial symptoms of rabies are headache, fever, sore throat, pain during swallowing anything solid. But later the person suffering from rabies goes through a lot of trouble. His behavior becomes unusual and aggressive. Due to paralytic effects in the pharyngeal muscle, eating is not possible. The patient runs away from water. Saliva keeps dripping from the mouth.


The patient swallows nothing due to the paralytic effect in the pharyngeal muscle. Malnutrition occurs. Gradually paralysis spreads throughout the body. Dies within a few days from respiratory obstruction. 




WHO report:



Rabies is an infectious viral disease that is almost always fatal following the onset of clinical symptoms. In up to 99% of cases, domestic dogs are responsible for rabies virus transmission to humans. Yet, rabies can affect both domestic and wild animals. It is spread to people through bites or scratches, usually via saliva.
Rabies is present on all continents, except Antarctica, with over 95% of human deaths occurring in the Asia and Africa regions.



The rabies virus

The virus enters the tissue during a bite, skin wounds, or abrasion from an infected animal. though disease associated with saliva, the urine, lymph, blood, or milk may be equally infectious. In 1978 a woman died of rabies in Boise, Idaho, due to a cornea transplant from an infected person.



Incubation period

The incubation period for rabies varies according to the number of virions introduced to the wound and the wound's proximity to the central nervous system.it may vary from six days to one year and shorter in children than adults.


Symptoms

The sign and symptoms of rabies are as follows



Early sign
  1. Tingling
  2. Burning
  3. Coldness
  4. Fever
  5. Headache.


Later sign
  1. Due to increased muscle tone, the patient becomes alert
  2. Aggressive
  3. Show unusual behavior
  4. Due to paralytic effects in pharyngeal muscle, difficulty in swallowing is felt
  5. Salivation become profuse
  6. Saliva drips, from the mouth
  7. Cannot be swallowed
  8. The paralysis spreads
  9. Death occurs within a few days by respiration inhibition.


Hydrophobia

hydrophobia means fear of water 




Causes

The rabies virus belongs to the group of viruses called lyssaviruses which can infect mammals.



Diagnosis

The tests used to confirm of rabies virus
  1. Skin biopsy
  2. Saliva test
  3. Lumbar puncture
  4. Blood test.



Prevention of rabies

The good thing is that this disease has become a vaccine. And is available in all countries.

Get vaccinated immediately after animal bites. This is the most effective way to stop it. If possible, gather information about the animal. To know whether the animal has been vaccinated or not. If you have pets in your house, then get them vaccinated. It is necessary to protect the whole family.
If you run a farmhouse, or if you want to come to such a place, then get yourself vaccinated in advance.


Wash the wound thoroughly with soap. Apply antiseptic cream. Also, see a doctor immediately.

Serum-containing anti-rabies antibodies are injected into the base of the wound in the hospital. Also, tetanus injection is given. The combination of vaccine and antibody is injected to neutralize the virus before it reaches the central nervous system.



Pre-exposure vaccination

A vaccine that protects against rabies is for those people who are at risk. the rabies vaccine available as a human diploid cell vaccine HDCV, purified chick embryo cell vaccine PCECV, and purified Vero cell rabies vaccine PVRV the vaccine may be administered by intramuscular or intradermal.


Post explore prophylaxis - PEP

Immunization or sero vaccine therapy is very effective for post-exposure. and administered immediately after exposure.  

एक टिप्पणी भेजें

4 टिप्पणियाँ

  1. There are many blogs I have read. But when I read Your Blogs I have found such useful information, fresh content with such amazing editing everything is superb in your blog. Thank you so much for sharing this useful and informative information with us.

    online doctor appointment

    जवाब देंहटाएं
  2. There are many blogs I have read. But when I read Your Blogs I have found such useful information, fresh content with such amazing editing everything is superb in your blog. Thank you so much for sharing this useful and informative information with us.

    online doctor appointment

    जवाब देंहटाएं
  3. I found this blog informative or very useful for me. I suggest everyone, once you should go through this.

    आँखों की कमजोरी के लक्षण

    जवाब देंहटाएं
  4. I found this blog informative or very useful for me. I suggest everyone, once you should go through this.

    आँखों की कमजोरी के लक्षण

    जवाब देंहटाएं

please do not send a spasm massage.